Miss Nina Billows
PhD Student
Department: Comparative Biomedical Sciences
Campus: Hawkshead
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Machine learning algorithms for predicting drug resistance against tuberculosis in people
Tuberculosis disease (TB), caused by Mycobacterium tuberculosis, is an important global public health issue, and its drug resistance, caused by genetic mutations in the M. tuberculosis genome, poses serious challenges for effective control. Current molecular diagnostic tests are imperfect as they do not target all resistance mechanisms and drugs, nor do they inform on transmission clusters, and are therefore unable to guide completely effective individualised therapy.