Dr Jonathan Williams
BVSc PhD PGCert(VetEd) FHEA Dipl.ECVP MRCVS
Senior Lecturer in Anatomic Pathology
Department: Pathobiology & Population Sciences
Campus: Hawkshead
Research Groups: CPCS (Research Programme)
Jonathan is a Senior Lecturer in Veterinary Anatomic Pathology at the ·¬ÇÑapp and Head of Pathology at the RVC. He is a Diplomate of the European College of Veterinary Pathologists (ECVP) and a Royal College of Veterinary Surgeons (RCVS) and European (EBVS) Recognised Specialist in Veterinary Pathology. He has also completed the Postgraduate Certificate in Veterinary Education and is a Fellow of the Higher Education Academy (FHEA).
Jonathan graduated from Bristol Vet School in 2005. He spent a brief time in mixed practice and then started a residency in veterinary pathology in 2006 at Liverpool Vet School. He became a Diplomate of the European College of Veterinary Pathologists in 2010 and a clinician teacher at Leahurst Surveillance Centre. He completed his PhD investigating Pathological Epithelial Cell Shedding in the Small Intestine in 2013. He then became a post-doctoral researcher investigating NF-κB signalling in IBD until he moved to the RVC as Lecturer in Veterinary Anatomic Pathology in 2015. He is the Head of Pathology at the RVC and has previously been the Anatomic Pathology Residency Director and Intra Mural Rotations Director. Jonathan is a member of the of the European College of Veterinary Pathologists (ECVP) and Innovation and New Technologies Task Force and European Society of Veterinary Pathologists (ESVP), and previously education sub-committee scientific organiser for the Mouse Models of Disease conferences and BSTP Annual Scientific Meeting.
Jonathan’s research interests are in in digital pathology and computational approaches to pathology including artifical intelligence analysis of whole slide images. He also has special interests in intestinal epithelial signalling and cell death mechanisms in the context of gut barrier dysfunction and intestinal epithilial dynamics and how intestinal bacterial populations interact with the epithelial and immune cell compartments in health and disease. He also has a special interest in investigating micro-RNAs as biomarkers of disease.
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Jonathan is the Head of Pathology at the RVC and has previously been the Anatomic Pathology Residency Director and Intra Mural Rotations Director. Jonathan lectures on gastrointestinal, hepatic and pacreatic pathology as well as pathology of the endocrine system. He also lectures on the principles and applications of pathology on the Bachelor of Veterinary Medicine, and Bachelor of Biological Sciences pathology courses. His teaching responsibilities include supervising Senior Clinical Training Scholars in Veterinary Pathology that are preparing for specialist qualifications in pathology and research students at PhD and undergraduate levels. He is also the Principles of Pathology unit organiser and deputy leader for the Imaging of Disease Module (BSc Biological Sciences), and deputy leader for the applications of pathology module for the BSc in comparative pathology.
Jonathan participates in the clinical surgical biopsy and post mortem diagnostic service of the RVC, and is involved in training the senior clinical training scholars in anatomic pathology.
Jonathan is a member of the of the European College of Veterinary Pathologists (ECVP) and Innovation and New Technologies Task Force , European Society of Veterinary Pathologists (ESVP), British Society of Veterinary Pathology (BSVP), British Society of Toxicological Pathology (BSTP) and previously education sub-committee scientific organiser for the BSTP Annual Scientific and Pathology of Mouse Models of Disease Meetings.
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A Multi-disciplinary Approach to Investigating Canine Diffuse Large B cell Lymphoma
We propose to better define genetic subtypes of canine lymphoma and characterising response to treatment of the different subtypes through a combination of more accurate phenotyping of lymphomas by integrating a) advanced image analysis b) genome sequencing, and c) total RNA sequencing (including micro-RNA sequencing).